TGBSL explained: In the second book of the semi-autobiographical series describing the progress of an Edinburgh medical graduate, Colin Douglas describes his hero, David Campbell’s, involvement with medical research. The book’s title is “The Greatest Breakthrough Since Lunchtime“ and the cynic in me always remembers it when I read headlines like these. I insist that I have a huge regard for our researchers, having watched my brother persevere with his work for years and now my son wrestle with a PhD I know that it is something to which I am not suited at all.
1 Ultra-tough antibiotic to fight superbugs
US scientists have re-engineered a vital antibiotic in a bid to wipe out one of the world’s most threatening superbugs. Their new version of vancomycin is designed to be ultra-tough and appears to be a thousand times more potent than the old drug, PNAS journal reports. It fights bacteria in three different ways, making it much less likely that the bugs can dodge the attack. It is yet to be tested in animals and people, however. The Scripps Research Institute team hope the drug will be ready for use within five years if it passes more tests….
BBC Report HERE
2 Common periodontal pathogen may interfere with conception in women
According to a study carried out at the University of Helsinki, Finland, a common periodontal pathogen may delay conception in young women. This finding is novel: previous studies have shown that periodontal diseases may be a risk for general health, but no data on the influence of periodontal bacteria on conception or becoming pregnant have been available….
“Our results encourage young women of fertile age to take care of their oral health and attend periodontal evaluations regularly”, says periodontist and researcher Susanna Paju, University of Helsinki….
Medical News Today HERE
3 Study: Use of prefabricated blood vessels may revolutionize root canals
While root canals are effective in saving a tooth that has become infected or decayed, this age-old procedure may cause teeth to become brittle and susceptible to fracture over time. Now researchers at OHSU in Portland, Oregon, have developed a process by which they can engineer new blood vessels in teeth, creating better long-term outcomes for patients and clinicians….
Full story HERE
4 Visiting virtual beach improves patient experiences during dental procedures
Imagine walking along a South Devon beach on a lovely day. The waves are lapping on the shore, rabbits are scurrying in the undergrowth, and the bells of the local church are mingling with the calls of the seagulls. Then, as you turn to continue along the coast path feeling calm and relaxed you suddenly hear your dentist say “Fine, all done, you can take the headset off now”. For patients at one dental practice in Devon, England, such Virtual Reality encounters are resulting in demonstrably better experiences in the dentist’s chair….
Full story HERE
5 Study: Blocking yeast-bacteria interaction may prevent severe biofilms that cause childhood tooth decay
Though most tooth decay can be blamed on bacteria, such as Streptococcus mutans, the fungus Candida albicans may be a joint culprit in an alarmingly common form of severe tooth decay affecting toddlers known as early childhood caries.
In earlier research, a team from the University of Pennsylvania School of Dental Medicine had found that C. albicans, a type of yeast, took advantage of an enzyme produced by S. mutans to form a particularly intractable biofilm. In a new study, the researchers have pinpointed the surface molecules on the fungus that interact with the bacterially-derived protein. Blocking that interaction impaired the ability of yeast to form a biofilm with S. mutans on the tooth surface, pointing to a novel therapeutic strategy….
Read more HERE