In case you missed – TGBSL #31

TGBSL explained: In the second book of the semi-autobiographical series describing the progress of an Edinburgh medical graduate, Colin Douglas describes his hero, David Campbell’s, involvement with medical research. The book’s title is “The Greatest Breakthrough Since Lunchtime“ and the cynic in me always remembers it when I read headlines like these. I insist that I have a huge regard for our researchers, having watched my brother persevere with his work for years and now my son wrestle with a PhD I know that it is something to which I am not suited at all. I bow to your diligence and dedication.

1) Study: Blocking yeast-bacteria interaction may prevent severe biofilms that cause childhood tooth decay

Though most tooth decay can be blamed on bacteria, such as Streptococcus mutans, the fungus Candida albicans may be a joint culprit in an alarmingly common form of severe tooth decay affecting toddlers known as early childhood caries.

“Instead of just targeting bacteria to treat early childhood caries, we may also want to target the fungi,” said Hyun (Michel) Koo, senior author on the study and a professor in the Department of Orthodontics and Divisions of Pediatric Dentistry and Community Oral Health. “Our data provide hints that you might not need to use a broad spectrum antimicrobial and might be able to target the enzyme or cell wall of the fungi to disrupt the plaque biofilm formation.”

Full article HERE

2) Which is better Invisalign or Fixed Appliances: Part 2: Does this new systematic review help?

This is the second of two posts on the effectiveness of Invisalign and Fixed Appliances. Last week I looked at a retrospective study and this week I will look at a new systematic review.

A lot of people read this post and generated a number of comments in the blog comments section and on other forms of social media. In my post last week, I pointed out that the study was retrospective and this meant that we needed to be cautious about the conclusions because of the potential for bias. Nevertheless, I still felt that the study provided us with some useful information. Just as I finished this post, I came across this new systematic review. I would like to discuss whether this helps us further. Full article HERE

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